Once-Promising Diabetes Drugs’ Side-Effects Can be Limited, Study Finds
Altering the activity of the PPARg receptor could limit the side-effects of a useful group of diabetes drugs, TZDs.
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Memory Strength Dependent on Abundance of ‘Package’ Deliveries, Study Shows
The number of vesicles at specific types of synapses lead to better memory formation, Davis' team discovered.
Opioid Users Could Benefit From Meth-Relapse Prevention Strategy, Study Finds
Professor Courtney Miller is developing a compound designed to directly target neurons involved in methamphetamine cravings. Photo by Scott Wiseman. JUPITER, FL – New research raises the possibility that a wider group of people in recovery from substance use disorders may benefit from a relapse-prevention compound designed by UF Scripps…
Two-Pronged Antibodies Draw Immune Killers Directly to Cancer Cells
The structure of the ROR1-binding arm of the bi-specific antibody in complex with ROR1 was determined by X-ray crystallography. Our immune system’s arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system. In a study in PNAS, Immunology…
Tumor-Like Spheres Help Scientists Discover Smarter Cancer Drugs
The spheroids mimic what might happen in a tumor: Some cells are on the outside and some are on the inside.
Your Immune System Holds the Line Against Repeat Invaders, Thanks to This Molecule
Researchers found a transcription factor called Runx3 puts dividing T cells on track to becoming memory T cells.
To Forget or to Remember? Memory Depends on Subtle Brain Signals, Study Finds
November 21, 2017 The fragrance of hot pumpkin pie can bring back pleasant memories of holidays past, while the scent of an antiseptic hospital room may cause a shudder. The power of odors to activate memories both pleasing and aversive exists in many animals, from humans to the humble fruit…
New Potential Painkillers Reduce Overdose Risk
JUPITER, FL – Scientists at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology have developed new opioid pain relievers that reduce pain on par with morphine but do not slow or stop breathing—the cause of opiate overdose. The research, published today in the journal Cell, describes a…
