expanding knowledge Lab news from The Wertheim UF Scripps Institute

Where scientists push the boundaries of human knowledge to solve humanity’s most pressing health challenges. Read about our latest discoveries, awards and announcements below.

Common Water Pill May Help HIV Medicines Work…

An FDA‑approved medication called spironolactone, often prescribed as a diuretic, or water pill, for heart and blood pressure conditions, may be a…

Susana Valente, Ph.D., chairs the immunology and microbiology department at The Wertheim UF Scripps Institute. Photo by Scott Wiseman.

Ambassador Council Formed to Further High-Impact…

Florida’s former CFO, Jeff Atwater, will chair the new Ambassador Council, joining Vice Chair Marti LaTour and nine other leaders in business, law…

spire

Scientists Blaze New Path to Fighting Viral…

Mapping vulnerabilities in the SARS-CoV-2 genome, made of RNA, reveals a path to fighting more than COVID-19.

Chemist Matthew Disney, Ph.D., reviews disease-causing RNA structures and possible binding pockets with his lab members at The Wertheim UF Scripps Institute in Jupiter, Florida.

Structure of Factor Involved in Major Depression Solved

Historically, GPR158 hasn’t been easy to study. It is called an “orphan receptor” because scientists haven’t yet identified the molecule responsible for turning its signaling function “on” in a manner similar to flipping a switch. It may play a role in depression and anxiety.

The CryoEM structure of GPR158, involved in mood disorders, from Martemyanov lab.

Potential ALS, Dementia Drug Targets RNA

The successful compound works by binding tightly to the disease-causing RNA in multiple places, while also attracting an enzyme that eliminates RNAs.

Induced neurons derived from ALS patients helped scientists test their compounds.

Wiring the Eyes to the Brain for Color Vision

Martemyanov lab at UF Scripps solves the mystery of how cones form their distinctive brain connections, giving humans and other animals their ability to see colors. 

Mouse retinal neurons from Martemyanov lab at UF Scripps.

Discovery Offers New Arthritis Target

Reactivating chondrocytes, the cells that create cartilage, may offer a way to regenerate the joint cushions that degrade with age.

Griffin

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The Wertheim UF Scripps Institute maintains an extensive image and video library. For access to content, or to arrange interviews with scientists, contact Stacey DeLoye, 561-228-2551. Off hours, the UF Health Communications team's main phone number is answered 24 hours a day, seven days a week. For assistance, call 352-273-5810.


Public Events

biotechnology pioneer

Movie Night: Cracking the Code

Please join us for a special movie night at the institute on Friday, Nov. 14 at 5 p.m., when we will screen the newly released documentary chronicling the life and career of Nobel laureate Phil Sharp, covering his groundbreaking RNA biology discovery that redefined how we understand genes and genetic disorders, with discussion led by Matthew Disney, Ph.D.

public lecture

Outsmarting Cancer: Lessons from Nature

Help recognize Cancer Prevention Month this February by attending a memorable lecture devoted to exploring nature’s lessons for cancer treatment and prevention. The discussion starts at 6 p.m. on Thursday, Feb. 5, 2026, at The Wertheim UF Scripps Institute, located at 120 Scripps Way; Jupiter, Florida.