expanding knowledge Lab news from The Wertheim UF Scripps Institute

Where scientists push the boundaries of human knowledge to solve humanity’s most pressing health challenges. Read about our latest discoveries, awards and announcements below.

Structure of Factor Involved in Major Depression Solved

Historically, GPR158 hasn’t been easy to study. It is called an “orphan receptor” because scientists haven’t yet identified the molecule responsible for turning its signaling function “on” in a manner similar to flipping a switch. It may play a role in depression and anxiety.

The CryoEM structure of GPR158, involved in mood disorders, from Martemyanov lab.

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Public Events

the wertheim uf scripps 2024 innovation lectures

Outsmarting Cancer

Scientists pushing the boundaries of cancer research gathered at the institute on Wednesday, January 17, 2024, for a panel discussion with Ambassador Nancy Brinker, founder of Susan G. Komen and the Promise Fund of Florida.

building the innovation ecosystem

Innovating for Cures

On Feb. 28, 2024, innovators, investors and donors discussed the types of support needed to drive progress for diseases with unmet medical needs.