Scientists have discovered two useful new enzymes which may help them create medicines for cancer and other conditions. The enzymes were found in the Natural Products Discovery Center collection.
A team led by chemistry professor Ben Shen, Ph.D., discovered a potent anti-cancer compound within the institute's natural products collection. It has been connected to a precise cancer-seeking antibody with an innovative linker molecule.
Enediynes can bind and break DNA, leading to cell death. As a result, they have enormous potential as antibiotics and cancer drugs. A new study reveals how nature assembles them.
“The great biosynthetic potential of nature has been explored in a limited way until now. By advancing the technologies needed to sequence large strain collections, such as the one here, we can begin to realize the full potential of this resource to benefit humanity.” Ben Shen, Ph.D. The…