Kendall Nettles, Ph.D., employs computer models to reveal how hormones, the body’s chemical messengers, and their receptors work together. The goal? To tackle real-world medical problems, including cancer drug resistance. Kendall Nettles, Ph.D., uses structural biology to improve treatments of hormone dependent cancers. Exploring…
"Discovering new medicines is challenging work that requires the expertise of many. There are real synergies for our scientists and students as we build collaboration among departments," said Matthew Disney, Ph.D., chair of The Wertheim UF Scripps chemistry department.
By distorting estrogen receptor shape in two different ways, compounds offer a two-for-one punch to estrogen-sensitive cancer cells. Kendall Nettles, PhD, (center) meets with two students in his lab, Jacqline Njeri (left) and Charles Min (right). Nettles and colleagues designed drug-like molecules that appear to fight estrogen-sensitive breast cancer in…
