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Two-Pronged Antibodies Draw Immune Killers Directly to Cancer Cells

The structure of the ROR1-binding arm of the bi-specific antibody in complex with ROR1 was determined by X-ray crystallography. Our immune system’s arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system. In a study in PNAS, Immunology and Microbiology…