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Inflammatory Lung Disease Risk Tied to Biomarkers

From the journal Therapeutic Advances in Respiratory Disease. During the pandemic, a primary cause of death for people hospitalized with COVID-19 was acute respiratory distress syndrome, or ARDS. A lack of effective medications has been an ongoing problem, including several clinical trial failures. A team led by…

What is NAMPT, and How Does it Regulate Inflammation?

When Dr. Joe G.N. “Skip” Garcia, M.D., was director of pulmonary and critical care medicine at Johns Hopkins University, his laboratory identified NAMPT (nicotinamide phosphoribosyltransferase) as a master regulator of inflammation and innate immunity. Inside the cell, NAMPT is an enzyme that plays a crucial role in…

Following Free Radicals With Finesse

A bioresponsive sensor from Carroll lab activates antioxidants only when needed and provides a tool for studying free radicals' role in disease.

Toward Safer Steroids

Scientists devise process for making precision anti-inflammatory medicines with fewer side-effects at UF Scripps Biomedical Research in Jupiter, Florida.