Half of glioblastoma patients have a subtype that doesn’t respond to any approved cancer drugs. A new experimental treatment from The Wertheim UF Scripps Institute shows promise in mouse studies. Clinical trials are coming soon.
Patrick Griffin, Ph.D., has dedicated his career to understanding the molecules of life in pursuit of treatments for cancer, diabetes, osteoporosis, obesity and more. Wertheim UF Scripps Scientific Director and Professor Patrick Griffin, Ph.D., helped develop a technique called HDX-MS that solves the challenge of…
Courtney Miller, Ph.D., is pioneering new drug discoveries for brain cancer, addiction and PTSD, all through a powerful protein family called myosin. By targeting myosin motor proteins in the brain, Courtney Miller, Ph.D., is developing new therapies to disrupt relapse, trauma and…
"Discovering new medicines is challenging work that requires the expertise of many. There are real synergies for our scientists and students as we build collaboration among departments," said Matthew Disney, Ph.D., chair of The Wertheim UF Scripps chemistry department.
A Parkinson's disease project from the lab of chemist Matthew D. Disney, Ph.D., has received a boost from a nonprofit focused on helping scientists translate their discoveries into treatments.
Children born with a damaged gene needed for healthy brain development, SYNGAP1, experience seizures, sensory processing disorders, difficulty speaking, intellectual disability, and autism-like behaviors. It’s a condition without any treatments, one that’s hard both on parents and children, said Gavin Rumbaugh, Ph.D., a neuroscientist at The Herbert Wertheim…
Predicting who could benefit from a given drug has been difficult. An international team led by neuroscientist Kirill Martemyanov, Ph.D., is training AI to assist.
The most effective pain relievers lose power over time. Scientists discover a gene that controls cholesterol in the cell membrane plays a key role.
A trailblazing scientist targets ALS, myotonic dystrophy, Parkinson’s, metastatic breast cancer, viral diseases and more by attacking key RNA, preventing disease-causing genes from being expressed in the first place.
The findings show it is possible to substantially accelerate the drug discovery process. The technique opens new doors to treating diseases by targeting their RNA processes, said Disney.
