HiPerGator Supercomputer Accelerates Diabetes Drug Discovery
Compounds able to reprogram insulin-resistant cells into a healthier state, with reduced side effects, are described in a new paper from Griffin lab.
Posts tagged as
Drug Discovery
Mapping Hormone Signaling to Outsmart Cancer Resistance
Kendall Nettles, Ph.D., applies detailed 3-D views and computer models to reveal how hormones, the body’s chemical messengers, and their receptors work. The goal? To tackle real‑world medical problems, including cancer drug resistance. Nettles’ lab works to translate molecular-level discoveries into better, safer medicines. Exploring the…
High-Speed Science: Using Robotics to Tackle the Toughest Challenges in Medicine
Timothy Spicer, Ph.D., and Louis Scampavia, Ph.D., use robotics and biochemistry to unearth potential new medicines. When scientists discover something new about a disease, it presents an exciting opportunity to find a new treatment. But where to start? Discovering the needle in the haystack…
Common Water Pill May Help HIV Medicines Work Faster and Reduce Inflammation, Early Study Suggests
An FDA‑approved medication called spironolactone, often prescribed as a diuretic, or water pill, for heart and blood pressure conditions, may be a useful add‑on to the standard HIV treatment, a new study shows.
A Special Place to Address Rare Diseases
The Journey from Molecule to Medicine – A Photo Tour Click on the arrows to see the path a discovery takes toward becoming a potential treatment. Image Gallery Chemist Matthew Disney’s group develops new ways to find medicines that act on disease-causing RNA.… Louis Scampavia, Ph.D., and Timothy Spicer, Ph.D.,…
Scientists Blaze New Path to Fighting Viral Diseases
Mapping vulnerabilities in the SARS-CoV-2 genome, made of RNA, reveals a path to fighting more than COVID-19.
Chemist Zhonglin Liu, Ph.D., Brings Chemical Proteomics Expertise to Jupiter
Liu’s research focuses on the discovery of small molecules for human proteins, as well as the functional characterization of these proteins in physiological and disease contexts.
Scientists Wipe Out Aggressive Brain Cancer Tumors by Targeting Cellular ‘Motors’
Half of glioblastoma patients have a subtype that doesn’t respond to any approved cancer drugs. A new experimental treatment from The Wertheim UF Scripps Institute shows promise in mouse studies. Clinical trials are coming soon.
Exploring Life at the Molecular Level to Invent Better Treatments
Patrick Griffin, Ph.D., has dedicated his career to understanding the molecules of life in pursuit of treatments for cancer, diabetes, osteoporosis, obesity and more. Wertheim UF Scripps Scientific Director and Professor Patrick Griffin, Ph.D., helped develop a technique called HDX-MS that solves the challenge of…
The Machinery of Disease: Scientist Invents a ‘Molecular Wrench’ That Thwarts Cancer
Courtney Miller, Ph.D., is pioneering new drug discoveries for brain cancer, addiction and PTSD, all through a powerful protein family called myosin. By targeting myosin motor proteins in the brain, Courtney Miller, Ph.D., is developing new therapies to disrupt relapse, trauma and…