AI can help us search enormous numbers of chemical structures. But it cannot look at a patient waiting for a medicine and decide which problem is worth a life's work.
A new discovery from the lab of chemist Matthew Disney, Ph.D., takes its inspiration from Greek mythology. The compound is a chimera, and it battles a toxic cause of Parkinson's in two ways.
The scientists’ approach directs cells’ recycling enzymes to cancer genes’ RNA and cuts up key segments to prevent them from doing harm. The tactic worked against the MYC cancer gene, and also two other challenging cancer genes.
January 17-18, 2023 The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology Rodney B. Fink Auditorium 120 Scripps Way, Jupiter, Florida 33458 RNA: From Biology to Drug Discovery See RNA Symposium Highlights and Photos…
A trailblazing scientist targets ALS, myotonic dystrophy, Parkinson’s, metastatic breast cancer, viral diseases and more by attacking key RNA, preventing disease-causing genes from being expressed in the first place.
The findings show it is possible to substantially accelerate the drug discovery process. The technique opens new doors to treating diseases by targeting their RNA processes, said Disney.
Alicia Angelbello, Ph.D., a student of the Skaggs Graduate School, studied with UF Scripps Chemistry Department Chair Matthew Disney, Ph.D. She has been awarded the American Chemical Society’s Nobel Signature Award. Wertheim UF Scripps Chemist Matthew Disney and Skaggs Graduate School student Alicia Angelbello devised a way to potentially treat…
Like a carpenter switching drill bits depending on the job at hand, scientists at Scripps Research in Florida have changed an investigational medicine’s activity by swapping in different molecular tools, in the process, showing a potential new way to address multiple incurable diseases.
