Kendall Nettles, Ph.D., applies detailed 3-D views and computer models to reveal how hormones, the body’s chemical messengers, and their receptors work. The goal? To tackle real‑world medical problems, including cancer drug resistance. Nettles’ lab works to translate molecular-level discoveries into better, safer medicines. Exploring the…
Timothy Spicer, Ph.D., and Louis Scampavia, Ph.D., use robotics and biochemistry to unearth potential new medicines. When scientists discover something new about a disease, it presents an exciting opportunity to find a new treatment. But where to start? Discovering the needle in the haystack…
The Journey from Molecule to Medicine – A Photo Tour Click on the arrows to see the path a discovery takes toward becoming a potential treatment. Image Gallery Chemist Matthew Disney’s group develops new ways to find medicines that act on disease-causing RNA.… Louis Scampavia, Ph.D., and Timothy Spicer, Ph.D.,…
stopping DiSease by understanding its root cause…
Donna Zhang, Ph.D., has dedicated her career to unraveling how cells’ defense system against oxidative stress, controlled by a gene called NRF2, can be strategically activated to prevent disease — or disarmed to help destroy cancer cells. Donna Zhang, Ph.D. The Big Picture What if…
"These grants highlight The Wertheim UF Scripps Institute’s unique expertise in areas that include neuroscience, immunology, biochemistry, drug discovery and RNA therapeutics,” said Scientific Director Patrick Griffin, Ph.D.
Meet the speakers…
A cancer-killing compound, called tiancimycin, combined with a cancer-seeking antibody, shows promise against an aggressive type of lymphoma.
Half of glioblastoma patients have a subtype that doesn’t respond to any approved cancer drugs. A new experimental treatment from The Wertheim UF Scripps Institute shows promise in mouse studies. Clinical trials are coming soon.
Michalina Janiszewska, Ph.D., Explores how cancer evolves – and how to outmaneuver it. Cancer is a moving target, constantly adapting, evolving and resisting treatment. Cancer biologist Michalina Janiszewska, Ph.D., of The Wertheim UF Scripps Institute, studies how tumors change over time, and how this…
