Joe G.N. Garcia, MD
Associate Vice President for Research
About Joe G.N. Garcia
Dr. Joe G. N. “Skip” Garcia is a renowned pulmonary physician-scientist and a distinguished figure in the field of medicine. He currently holds several prestigious positions, including being an endowed professor and the Director of the Center for Inflammation Sciences and Systems Medicine at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology. Additionally, he serves as the Associate Vice President of Research at the University of Florida. Dr. Garcia’s contributions to the medical community have been recognized by his election as a member of the National Academy of Medicine.
Dr. Garcia’s expertise lies in the genetic basis of lung disease and the prevention and treatment of inflammatory lung injury. He is widely acknowledged for his groundbreaking work in developing novel biomarkers and therapies for critically ill patients affected by acute inflammatory lung disease. Furthermore, Dr. Garcia’s research efforts extend to addressing health disparities among vulnerable populations. His remarkable achievements are evident in his extensive publication record, which includes over 575 peer-reviewed publications. Dr. Garcia’s dedication to advancing medical knowledge is reflected in his leadership of large federally-funded programs and his impressive portfolio of NIH-sponsored research.
Additional Positions:
Director
2023 – Current
·
Center for Inflammation Sciences & Systems Medicine, UF Scripps
Professor of Medicine
2023 – Current
·
University of Florida
Related Links:
Research Profile
Dr. Garcia’s expertise extends to the genetic basis of inflammatory lung disease, with a particular focus on health disparities, as well as the mechanistic understanding of lung vascular permeability. Through bench-to-bedside approaches, his laboratory has conducted innovative research to develop methods aimed at preventing vascular leak, restoring endothelial cell barrier function, and maintaining vascular integrity.
Given their deep knowledge of lung inflammation and vascular permeability, Dr. Garcia’s lab has also explored the role of lung vasculature in the development of lung metastases. Leveraging their expertise in genomics, they have identified vascular genes that are crucial participants in both inflammatory lung injury and cancer development. Their investigations have led to the development of lung endothelial inflammatory gene expression profiles and diagnostic gene signatures influenced by key genes such as MYLK and NAMPT, which have implications for lung and breast cancer prognosis.
Furthermore, their work with NAMPT has resulted in the development of a therapeutic NAMPT neutralizing antibody. This antibody has shown promise in treating various cancers, including lung cancer, melanoma, and chronic lymphocytic leukemia.
Additionally, Dr. Garcia’s laboratory is actively involved in studying the adverse effects of thoracic radiation and exploring strategies to mitigate radiation-induced pneumonitis, fibrosis, and vascular leak.
Publications
Academic Articles
2025
CYP4F11, an NRF2 Target Gene, Promotes Hepatocellular Carcinoma Cell Growth.
Molecular carcinogenesis.
64(7):1264-1274
[DOI] 10.1002/mc.23925.
[PMID] 40329467.
2025
eNAMPT Is a Novel DAMP and Therapeutic Target in Human and Murine Pulmonary Fibrosis.
American journal of respiratory cell and molecular biology.
[DOI] 10.1165/rcmb.2024-0342OC.
[PMID] 40126452.
2025
NEDD4 E3 ligase-catalyzed NAMPT ubiquitination and autophagy activation are essential for pyroptosis-independent NAMPT secretion in human monocytes.
Cell communication and signaling : CCS.
23(1)
[DOI] 10.1186/s12964-025-02164-5.
[PMID] 40159488.
2025
Predictive modeling of ARDS mortality integrating biomarker/cytokine, clinical and metabolomic data.
Translational research : the journal of laboratory and clinical medicine.
281:31-42
[DOI] 10.1016/j.trsl.2025.05.005.
[PMID] 40419238.
2024
A Razor’s Edge: Vascular Responses to Acute Inflammatory Lung Injury/Acute Respiratory Distress Syndrome.
Annual review of physiology.
86:505-529
[DOI] 10.1146/annurev-physiol-042222-030731.
[PMID] 38345908.
2024
Advanced hemodynamic and cluster analysis for identifying novel RV function subphenotypes in patients with pulmonary hypertension.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
43(5):755-770
[DOI] 10.1016/j.healun.2023.12.009.
[PMID] 38141893.
2024
An eNAMPT-neutralizing mAb reduces post-infarct myocardial fibrosis and left ventricular dysfunction.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
170
[DOI] 10.1016/j.biopha.2023.116103.
[PMID] 38160623.
2024
Circadian disruption dysregulates lung gene expression associated with inflammatory lung injury.
Frontiers in immunology.
15
[DOI] 10.3389/fimmu.2024.1348181.
[PMID] 38558813.
2024
Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension
Circulation.
150(4):302-316
[DOI] 10.1161/circulationaha.123.065304.
2024
Development of a cloud-based flow rate tool for eNAMPT biomarker detection
PNAS Nexus.
3(5)
[DOI] 10.1093/pnasnexus/pgae173.
[PMID] 38711808.
2024
eNAMPT is a novel therapeutic target for mitigation of coronary microvascular disease in type 2 diabetes.
Diabetologia.
67(9):1998-2011
[DOI] 10.1007/s00125-024-06201-9.
[PMID] 38898303.
2024
Extracellular Nicotinamide Phosphoribosyltransferase Is a Therapeutic Target in Experimental Necrotizing Enterocolitis
Biomedicines.
12(5)
[DOI] 10.3390/biomedicines12050970.
[PMID] 38790933.
2024
Genetic and epigenetic regulation of cortactin (CTTN) by inflammatory factors and mechanical stress in human lung endothelial cells.
Bioscience reports.
44(9)
[DOI] 10.1042/BSR20231934.
[PMID] 39162263.
2024
Pro- and anti-inflammatory cytokines: the hidden keys to autoimmune gastritis therapy.
Frontiers in pharmacology.
15
[DOI] 10.3389/fphar.2024.1450558.
[PMID] 39193325.
2024
Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report.
American journal of respiratory cell and molecular biology.
71(4):388-406
[DOI] 10.1165/rcmb.2024-0330ST.
[PMID] 39189891.
2023
A Least Absolute Shrinkage and Selection Operator-Derived Predictive Model for Postoperative Respiratory Failure in a Heterogeneous Adult Elective Surgery Patient Population
CHEST Critical Care.
1(3)
[DOI] 10.1016/j.chstcc.2023.100025.
[PMID] 38434477.
2023
Classification and Predictors of Right Ventricular Functional Recovery in Pulmonary Arterial Hypertension
Circulation: Heart Failure.
16(10)
[DOI] 10.1161/circheartfailure.123.010555.
2023
Classification and Predictors of Right Ventricular Functional Recovery in Pulmonary Arterial Hypertension.
medRxiv : the preprint server for health sciences.
[DOI] 10.1101/2023.02.15.23285974.
[PMID] 36824981.
2023
Development of a peripheral blood transcriptomic gene signature to predict bronchopulmonary dysplasia
American Journal of Physiology-Lung Cellular and Molecular Physiology.
324(1):L76-L87
[DOI] 10.1152/ajplung.00250.2022.
[PMID] 36472344.
2023
eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE Lung vasculitis and alveolar hemorrhage
Journal of Translational Autoimmunity.
6
[DOI] 10.1016/j.jtauto.2022.100181.
[PMID] 36619655.
2023
Examination of eQTL Polymorphisms Associated with Increased Risk of Progressive Complicated Sarcoidosis in European and African Descent Subjects.
European journal of respiratory medicine.
5(1):359-371
[PMID] 38390497.
2023
Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer.
Journal for immunotherapy of cancer.
11(10)
[DOI] 10.1136/jitc-2023-007010.
[PMID] 37880182.
2023
Involvement of eNAMPT/TLR4 inflammatory signaling in progression of non‐alcoholic fatty liver disease, steatohepatitis, and fibrosis
The FASEB Journal.
37(3)
[DOI] 10.1096/fj.202201972rr.
2023
Lamellipodia dynamics and microrheology in endothelial cell paracellular gap closure.
Biophysical journal.
122(24):4730-4747
[DOI] 10.1016/j.bpj.2023.11.016.
[PMID] 37978804.
2023
Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity
Therapeutic Advances in Respiratory Disease.
17
[DOI] 10.1177/17534666231181262.
[PMID] 37477094.
2023
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
Science Advances.
9(5)
[DOI] 10.1126/sciadv.ade9585.
[PMID] 36724221.
2023
SARS-CoV-2 infection dysregulates NAD metabolism.
Frontiers in immunology.
14
[DOI] 10.3389/fimmu.2023.1158455.
[PMID] 37457744.
2023
Targeting SELPLG/P‐selectin glycoprotein ligand 1 in preclinical ARDS: Genetic and epigenetic regulation of the SELPLG promoter
Pulmonary Circulation.
13(1)
[DOI] 10.1002/pul2.12206.
[PMID] 36873461.
2023
The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes.
Frontiers in physiology.
14
[DOI] 10.3389/fphys.2023.1129413.
[PMID] 37415908.
2023
The impact of intravenous dodecafluoropentane on a murine model of acute lung injury.
Intensive care medicine experimental.
11(1)
[DOI] 10.1186/s40635-023-00518-2.
[PMID] 37322298.
2023
The NRF2-p97-NRF2 negative feedback loop.
Redox biology.
65
[DOI] 10.1016/j.redox.2023.102839.
[PMID] 37573837.
2023
Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure.
Respiratory research.
24(1)
[DOI] 10.1186/s12931-023-02481-8.
[PMID] 37415141.
2022
A cortactin CTTN coding SNP contributes to lung vascular permeability and inflammatory disease severity in African descent subjects.
Translational research : the journal of laboratory and clinical medicine.
244:56-74
[DOI] 10.1016/j.trsl.2022.02.002.
[PMID] 35181549.
2022
A practical treatment for COVID-19 and the next pandemic.
Pharmacology research & perspectives.
10(4)
[DOI] 10.1002/prp2.988.
[PMID] 35837790.
2022
An Actin-, Cortactin- and Ena-VASP-Linked Complex Contributes to Endothelial Cell Focal Adhesion and Vascular Barrier Regulation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
56(4):329-339
[DOI] 10.33594/000000553.
[PMID] 35856787.
2022
Author Correction: Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.
Nature communications.
13(1)
[DOI] 10.1038/s41467-022-33381-y.
[PMID] 36433938.
2022
Biochemical and genomic identification of novel biomarkers in progressive sarcoidosis: HBEGF, eNAMPT, and ANG-2.
Frontiers in medicine.
9
[DOI] 10.3389/fmed.2022.1012827.
[PMID] 36388923.
2022
Circulating eNAMPT as a biomarker in the critically ill: acute pancreatitis, sepsis, trauma, and acute respiratory distress syndrome.
BMC anesthesiology.
22(1)
[DOI] 10.1186/s12871-022-01718-1.
[PMID] 35705899.
2022
Clinical Characteristics and Transplant-Free Survival Across the Spectrum of Pulmonary Vascular Disease.
Journal of the American College of Cardiology.
80(7):697-718
[DOI] 10.1016/j.jacc.2022.05.038.
[PMID] 35953136.
2022
Cortactin in Lung Cell Function and Disease
International Journal of Molecular Sciences.
23(9)
[DOI] 10.3390/ijms23094606.
[PMID] 35562995.
2022
Critical role for the lung endothelial nonmuscle myosin light‐chain kinase isoform in the severity of inflammatory murine lung injury
Pulmonary Circulation.
12(2)
[DOI] 10.1002/pul2.12061.
[PMID] 35514774.
2022
Cytokine profiling in pulmonary arterial hypertension: the role of redox homeostasis and sex.
Translational research : the journal of laboratory and clinical medicine.
247:1-18
[DOI] 10.1016/j.trsl.2022.03.013.
[PMID] 35405322.
2022
eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis
American Journal of Respiratory Cell and Molecular Biology.
66(5):497-509
[DOI] 10.1165/rcmb.2021-0357oc.
2022
eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury.
Frontiers in physiology.
13
[DOI] 10.3389/fphys.2022.916159.
[PMID] 35812318.
2022
eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling.
Scientific reports.
12(1)
[DOI] 10.1038/s41598-021-04444-9.
[PMID] 35027578.
2022
Incremental value of cardiopulmonary exercise testing in intermediate-risk pulmonary arterial hypertension.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
41(6):780-790
[DOI] 10.1016/j.healun.2022.02.021.
[PMID] 35414469.
2022
Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses.
Frontiers in physiology.
13
[DOI] 10.3389/fphys.2022.769325.
[PMID] 35250607.
2022
MRSA-induced endothelial permeability and acute lung injury are attenuated by FTY720 S-phosphonate
American Journal of Physiology-Lung Cellular and Molecular Physiology.
322(1):L149-L161
[DOI] 10.1152/ajplung.00100.2021.
[PMID] 35015568.
2022
NRF2 and Diabetes: The Good, the Bad, and the Complex.
Diabetes…
71(12):2463-2476
[DOI] 10.2337/db22-0623.
[PMID] 36409792.
2022
Predictive potential of ACE phenotyping in extrapulmonary sarcoidosis.
Respiratory research.
23(1)
[DOI] 10.1186/s12931-022-02145-z.
[PMID] 35996109.
2022
The Right Ventricular-Pulmonary Arterial Coupling and Diastolic Function Response to Therapy in Pulmonary Arterial Hypertension.
Chest.
161(4):1048-1059
[DOI] 10.1016/j.chest.2021.09.040.
[PMID] 34637777.
2022
TLR4 activation induces inflammatory vascular permeability via Dock1 targeting and NOX4 upregulation.
Biochimica et biophysica acta. Molecular basis of disease.
1868(12)
[DOI] 10.1016/j.bbadis.2022.166562.
[PMID] 36179995.
2021
A Humanized Monoclonal Antibody Targeting Extracellular Nicotinamide Phosphoribosyltransferase Prevents Aggressive Prostate Cancer Progression.
Pharmaceuticals (Basel, Switzerland).
14(12)
[DOI] 10.3390/ph14121322.
[PMID] 34959723.
2021
Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.
Nature communications.
12(1)
[DOI] 10.1038/s41467-021-27326-0.
[PMID] 34876579.
2021
Cohesive cancer invasion of the biophysical barrier of smooth muscle
Cancer and Metastasis Reviews.
40(1):205-219
[DOI] 10.1007/s10555-020-09950-2.
[PMID] 33398621.
2021
Cortactin Modulates Lung Endothelial Apoptosis Induced by Cigarette Smoke.
Cells.
10(11)
[DOI] 10.3390/cells10112869.
[PMID] 34831092.
2021
Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody.
The European respiratory journal.
57(5)
[DOI] 10.1183/13993003.02536-2020.
[PMID] 33243842.
2021
Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT‐neutralizing mAb
Pulmonary Circulation.
11(4):1-14
[DOI] 10.1177/20458940211059712.
[PMID] 34790349.
2021
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension
American Journal of Physiology-Cell Physiology.
321(6):C1010-C1027
[DOI] 10.1152/ajpcell.00147.2021.
[PMID] 34669509.
2021
Epitope mapping of novel monoclonal antibodies to human angiotensin I-converting enzyme.
Protein science : a publication of the Protein Society.
30(8):1577-1593
[DOI] 10.1002/pro.4091.
[PMID] 33931897.
2021
Erratum to Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction, Redox Biology 36 (2020) 101638.
Redox biology.
48
[DOI] 10.1016/j.redox.2021.102200.
[PMID] 34844898.
2021
Essential role for paxillin tyrosine phosphorylation in LPS-induced mitochondrial fission, ROS generation and lung endothelial barrier loss.
Scientific reports.
11(1)
[DOI] 10.1038/s41598-021-97006-y.
[PMID] 34475475.
2021
EVL is a novel focal adhesion protein involved in the regulation of cytoskeletal dynamics and vascular permeability
Pulmonary Circulation.
11(4):1-10
[DOI] 10.1177/20458940211049002.
[PMID] 34631011.
2021
Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress
Clinical Science.
135(7):963-977
[DOI] 10.1042/cs20201448.
2021
Identification of early and intermediate biomarkers for ARDS mortality by multi-omic approaches.
Scientific reports.
11(1)
[DOI] 10.1038/s41598-021-98053-1.
[PMID] 34556700.
2021
IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.
Blood.
137(9):1208-1218
[DOI] 10.1182/blood.2020005944.
[PMID] 33181835.
2021
Integrative omics provide biological and clinical insights into acute respiratory distress syndrome.
Intensive care medicine.
47(7):761-771
[DOI] 10.1007/s00134-021-06410-5.
[PMID] 34032881.
2021
MicroRNA and protein-coding gene expression analysis in idiopathic pulmonary fibrosis yields novel biomarker signatures associated to survival.
Translational research : the journal of laboratory and clinical medicine.
228:1-12
[DOI] 10.1016/j.trsl.2020.07.009.
[PMID] 32711186.
2021
NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review.
Journal of the American College of Cardiology.
77(16):2040-2052
[DOI] 10.1016/j.jacc.2021.02.056.
[PMID] 33888254.
2021
Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism.
Molecular metabolism.
51
[DOI] 10.1016/j.molmet.2021.101243.
[PMID] 33933676.
2021
Strategies to DAMPen COVID-19-mediated lung and systemic inflammation and vascular injury.
Translational research : the journal of laboratory and clinical medicine.
232:37-48
[DOI] 10.1016/j.trsl.2020.12.008.
[PMID] 33358868.
2021
Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis
European Respiratory Journal.
58(6)
[DOI] 10.1183/13993003.02950-2020.
[PMID] 34083402.
2021
TRPC6, a therapeutic target for pulmonary hypertension
American Journal of Physiology-Lung Cellular and Molecular Physiology.
321(6):L1161-L1182
[DOI] 10.1152/ajplung.00159.2021.
[PMID] 34704831.
2021
UCHL1, a deubiquitinating enzyme, regulates lung endothelial cell permeability in vitro and in vivo.
American journal of physiology. Lung cellular and molecular physiology.
320(4):L497-L507
[DOI] 10.1152/ajplung.00492.2020.
[PMID] 33438509.
2021
Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells.
Frontiers in physiology.
12
[DOI] 10.3389/fphys.2021.714785.
[PMID] 34408668.
2021
Whole-Blood Mitochondrial DNA Copies Are Associated With the Prognosis of Acute Respiratory Distress Syndrome After Sepsis.
Frontiers in immunology.
12
[DOI] 10.3389/fimmu.2021.737369.
[PMID] 34557198.
2020
Arg mediates LPS-induced disruption of the pulmonary endothelial barrier.
Vascular pharmacology.
128-129
[DOI] 10.1016/j.vph.2020.106677.
[PMID] 32240815.
2020
Clinical implications of idiopathic pulmonary arterial hypertension phenotypes defined by cluster analysis.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
39(4):310-320
[DOI] 10.1016/j.healun.2019.12.012.
[PMID] 32061507.
2020
Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas.
Respiratory research.
21(1)
[DOI] 10.1186/s12931-020-01537-3.
[PMID] 33276795.
2020
Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α
American Journal of Respiratory Cell and Molecular Biology.
63(1):92-103
[DOI] 10.1165/rcmb.2019-0164oc.
2020
Endothelial platelet‐derived growth factor‐mediated activation of smooth muscle platelet‐derived growth factor receptors in pulmonary arterial hypertension
Pulmonary Circulation.
10(3):1-15
[DOI] 10.1177/2045894020948470.
[PMID] 33294172.
2020
Genetic Admixture and Survival in Diverse Populations with Pulmonary Arterial Hypertension.
American journal of respiratory and critical care medicine.
201(11):1407-1415
[DOI] 10.1164/rccm.201907-1447OC.
[PMID] 31916850.
2020
In silico Docking Studies of Fingolimod and S1P1 Agonists.
Frontiers in pharmacology.
11
[DOI] 10.3389/fphar.2020.00247.
[PMID] 32210822.
2020
Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction.
Biophysical journal.
118(11):2769-2782
[DOI] 10.1016/j.bpj.2020.04.026.
[PMID] 32402244.
2020
More to Add to E-Cigarette Regulations: Unified Approaches.
Chest.
157(4):771-773
[DOI] 10.1016/j.chest.2019.11.024.
[PMID] 32252929.
2020
Nicotinamide phosphoribosyltransferase purification using SUMO expression system.
Analytical biochemistry.
598
[DOI] 10.1016/j.ab.2020.113597.
[PMID] 31982408.
2020
Role of secreted extracellular nicotinamide phosphoribosyltransferase (eNAMPT) in prostate cancer progression: Novel biomarker and therapeutic target.
EBioMedicine.
61
[DOI] 10.1016/j.ebiom.2020.103059.
[PMID] 33045468.
2020
Sphingosine‐1‐phosphate receptor‐independent lung endothelial cell barrier disruption induced by FTY720 regioisomers
Pulmonary Circulation.
10(1):1-10
[DOI] 10.1177/2045894020905521.
[PMID] 32095229.
2020
Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction.
Redox biology.
36
[DOI] 10.1016/j.redox.2020.101638.
[PMID] 32863203.
2020
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
British journal of pharmacology.
177(12):2743-2764
[DOI] 10.1111/bph.15000.
[PMID] 31976548.
2020
The acute respiratory distress syndrome biomarker pipeline: crippling gaps between discovery and clinical utility.
Translational research : the journal of laboratory and clinical medicine.
226:105-115
[DOI] 10.1016/j.trsl.2020.06.010.
[PMID] 32599095.
2020
Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes.
Pulmonary circulation.
10(4)
[DOI] 10.1177/2045894020968531.
[PMID] 33343881.
2019
Development of a biomarker mortality risk model in acute respiratory distress syndrome.
Critical care (London, England).
23(1)
[DOI] 10.1186/s13054-019-2697-x.
[PMID] 31842964.
2019
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology.
316(1):L216-L228
[DOI] 10.1152/ajplung.00538.2017.
[PMID] 30358436.
2019
EXPRESS: Surfing the Right Ventricular Pressure Waveform: Methods to assess Global, Systolic and Diastolic RV Function from a Clinical Right Heart Catheterization.
Pulmonary circulation.
10(1)
[DOI] 10.1177/2045894019850993.
[PMID] 31032737.
2019
Gene Editing of α6 Integrin Inhibits Muscle Invasive Networks and Increases Cell-Cell Biophysical Properties in Prostate Cancer.
Cancer research.
79(18):4703-4714
[DOI] 10.1158/0008-5472.CAN-19-0868.
[PMID] 31337652.
2019
Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
The Lancet. Respiratory medicine.
7(3):227-238
[DOI] 10.1016/S2213-2600(18)30409-0.
[PMID] 30527956.
2019
Genomic and Genetic Approaches to Deciphering Acute Respiratory Distress Syndrome Risk and Mortality.
Antioxidants & redox signaling.
31(14):1027-1052
[DOI] 10.1089/ars.2018.7701.
[PMID] 31016989.
2019
Integrin α6β4E variant is associated with actin and CD9 structures and modifies the biophysical properties of cell-cell and cell-extracellular matrix interactions.
Molecular biology of the cell.
30(7):838-850
[DOI] 10.1091/mbc.E18-10-0652.
[PMID] 30865564.
2019
Low Dose Carbon Monoxide Exposure in Idiopathic Pulmonary Fibrosis Produces a CO Signature Comprised of Oxidative Phosphorylation Genes.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-50585-3.
[PMID] 31615996.
2019
Measurement of exclusive photoproduction from protons in Pb collisions at .
The European physical journal. C, Particles and fields.
79(3)
[DOI] 10.1140/epjc/s10052-019-6774-8.
[PMID] 31007586.
2019
Tissue ACE phenotyping in lung cancer.
PloS one.
14(12)
[DOI] 10.1371/journal.pone.0226553.
[PMID] 31877149.
2018
A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis.
Chest.
153(1):94-104
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2018
An update on sphingosine-1-phosphate receptor 1 modulators.
Bioorganic & medicinal chemistry letters.
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2018
Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension.
The American journal of medicine.
131(6):702.e7-702.e13
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2018
Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
American journal of physiology. Lung cellular and molecular physiology.
314(2):L256-L275
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2018
Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor.
American journal of respiratory and critical care medicine.
197(11):1421-1432
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2018
LPS-induced Acute Lung Injury Involves NF-κB-mediated Downregulation of SOX18.
American journal of respiratory cell and molecular biology.
58(5):614-624
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2018
Measurement of associated Z + charm production in proton-proton collisions at .
The European physical journal. C, Particles and fields.
78(4)
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2018
Measurement of b hadron lifetimes in pp collisions at .
The European physical journal. C, Particles and fields.
78(6)
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2018
Measurement of prompt and nonprompt charmonium suppression in collisions at 5.02 .
The European physical journal. C, Particles and fields.
78(6)
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2018
Measurement of the cross section in pp collisions at and validation of lepton analysis techniques.
The European physical journal. C, Particles and fields.
78(9)
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2018
Measurement of the top quark mass with lepton+jets final states using collisions at .
The European physical journal. C, Particles and fields.
78(11)
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[PMID] 30881206.
2018
Measurements of the production cross section and the branching fraction, and constraints on anomalous triple gauge couplings at .
The European physical journal. C, Particles and fields.
78(2)
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2018
Myosin light chain kinase ( MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions.
Pulmonary circulation.
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2018
New cases of Glucose-6-Phosphate Dehydrogenase deficiency in Pulmonary Arterial Hypertension.
PloS one.
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2018
Novel Mechanism for Nicotinamide Phosphoribosyltransferase Inhibition of TNF-α-mediated Apoptosis in Human Lung Endothelial Cells.
American journal of respiratory cell and molecular biology.
59(1):36-44
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2018
Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension.
JACC. Basic to translational science.
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2018
RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression.
Proceedings of the National Academy of Sciences of the United States of America.
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2018
Search for new physics in dijet angular distributions using proton-proton collisions at and constraints on dark matter and other models.
The European physical journal. C, Particles and fields.
78(9)
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2018
Search for new physics in events with a leptonically decaying Z boson and a large transverse momentum imbalance in proton-proton collisions at = 13 .
The European physical journal. C, Particles and fields.
78(4)
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2018
Search for third-generation scalar leptoquarks decaying to a top quark and a lepton at .
The European physical journal. C, Particles and fields.
78(9)
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2018
Single nucleotide polymorphisms in the MYLKP1 pseudogene are associated with increased colon cancer risk in African Americans
PLOS ONE.
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[PMID] 30161129.
2018
The Splicing Factor hnRNPA1 Regulates Alternate Splicing of the MYLK Gene.
American journal of respiratory cell and molecular biology.
58(5):604-613
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[PMID] 29077485.
2017
A Transformative Approach to Academic Medicine: The Partnership Between the University of Arizona and Banner Health.
Academic medicine :, journal of the Association of American Medical Colleges…
92(1):20-22
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2017
An American Thoracic Society/National Heart, Lung, and Blood Institute Workshop Report: Addressing Respiratory Health Equality in the United States.
Annals of the American Thoracic Society.
14(5):814-826
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2017
Association of circulating transcriptomic profiles with mortality in sickle cell disease.
Blood.
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2017
Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH.
American journal of physiology. Lung cellular and molecular physiology.
312(3):L309-L325
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2017
Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia-induced pulmonary hypertension.
British journal of pharmacology.
174(22):4155-4172
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2017
Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related severity of acute lung injury.
American journal of physiology. Lung cellular and molecular physiology.
312(3):L297-L308
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2017
Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.
American journal of physiology. Lung cellular and molecular physiology.
312(4):L452-L476
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2017
Epigenetic contribution of the myosin light chain kinase gene to the risk for acute respiratory distress syndrome.
Translational research : the journal of laboratory and clinical medicine.
180:12-21
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2017
Health Disparities in Patients with Pulmonary Arterial Hypertension: A Blueprint for Action. An Official American Thoracic Society Statement.
American journal of respiratory and critical care medicine.
196(8):e32-e47
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2017
High Positive End-Expiratory Pressure Is Associated with Improved Survival in Obese Patients with Acute Respiratory Distress Syndrome.
The American journal of medicine.
130(2):207-213
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2017
How prostacyclin therapy improves right ventricular function in pulmonary arterial hypertension.
The European respiratory journal.
50(2)
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2017
Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury.
Free radical biology & medicine.
102:217-228
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2017
Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature.
Scientific reports.
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Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death (DCD).
Pulmonary circulation.
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Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation.
Free radical biology & medicine.
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2017
Measurement of the [Formula: see text] production cross section using events in the [Formula: see text] final state in pp collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
77(3)
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[PMID] 28408859.
2017
Measurement of the production cross section of a W boson in association with two b jets in pp collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
77(2)
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2017
Measurement of the triple-differential dijet cross section in proton-proton collisions at and constraints on parton distribution functions.
The European physical journal. C, Particles and fields.
77(11)
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2017
Measurement of the WZ production cross section in pp collisions at [Formula: see text] and 8[Formula: see text] and search for anomalous triple gauge couplings at [Formula: see text].
The European physical journal. C, Particles and fields.
77(4)
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[PMID] 28515665.
2017
Mechanical Stress and Single Nucleotide Variants Regulate Alternative Splicing of the MYLK Gene.
American journal of respiratory cell and molecular biology.
56(1):29-37
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2017
Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis.
American journal of respiratory and critical care medicine.
196(2):208-219
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2017
Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension.
Circulation.
135(16):1532-1546
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2017
Particulate matter disrupts human lung endothelial cell barrier integrity via Rho-dependent pathways.
Pulmonary circulation.
7(3):617-623
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2017
Search for dark matter produced in association with heavy-flavor quark pairs in proton-proton collisions at .
The European physical journal. C, Particles and fields.
77(12)
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2017
Search for heavy resonances that decay into a vector boson and a Higgs boson in hadronic final states at .
The European physical journal. C, Particles and fields.
77(9)
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2017
Search for physics beyond the standard model in events with two leptons of same sign, missing transverse momentum, and jets in proton-proton collisions at .
The European physical journal. C, Particles and fields.
77(9)
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2017
Shear-mediated platelet activation in the free flow: Perspectives on the emerging spectrum of cell mechanobiological mechanisms mediating cardiovascular implant thrombosis.
Journal of biomechanics.
50:20-25
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2017
Simvastatin-induced sphingosine 1-phosphate receptor 1 expression is KLF2-dependent in human lung endothelial cells.
Pulmonary circulation.
7(1):117-125
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2017
The ARP 2/3 complex mediates endothelial barrier function and recovery.
Pulmonary circulation.
7(1):200-210
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2017
The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression.
Journal of the American Chemical Society.
139(22):7456-7475
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2017
Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study.
The Lancet. Respiratory medicine.
5(11):857-868
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2016
“Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720”.
Chemistry and physics of lipids.
194:85-93
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2016
A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease.
Human molecular genetics.
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2016
Annexin A11 is associated with pulmonary fibrosis in African American patients with sarcoidosis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG.
33(4):418-422
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2016
Associations of Prolonged QTc in Sickle Cell Disease.
PloS one.
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2016
Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells.
American journal of respiratory cell and molecular biology.
55(2):275-87
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2016
ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells.
American journal of physiology. Cell physiology.
310(2):C99-114
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2016
Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner.
Scientific reports.
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2016
Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing.
Translational research : the journal of laboratory and clinical medicine.
168:22-39
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2016
Endotoxin- and mechanical stress-induced epigenetic changes in the regulation of the nicotinamide phosphoribosyltransferase promoter.
Pulmonary circulation.
6(4):539-544
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Event generator tunes obtained from underlying event and multiparton scattering measurements.
The European physical journal. C, Particles and fields.
76
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Expression profiling elucidates a molecular gene signature for pulmonary hypertension in sarcoidosis.
Pulmonary circulation.
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2016
Forward-backward asymmetry of Drell-Yan lepton pairs in pp collisions at [Formula: see text][Formula: see text].
The European physical journal. C, Particles and fields.
76(6)
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2016
Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease.
PloS one.
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2016
Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene.
The Journal of allergy and clinical immunology.
137(3):964-6
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2016
Lysozyme and bilirubin bind to ACE and regulate its conformation and shedding.
Scientific reports.
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Measurement of [Formula: see text] production with additional jet activity, including [Formula: see text] quark jets, in the dilepton decay channel using pp collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
76(7)
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2016
Measurement of differential cross sections for Higgs boson production in the diphoton decay channel in pp collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
76
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2016
Measurement of dijet azimuthal decorrelation in pp collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
76(10)
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2016
Measurement of inclusive jet production and nuclear modifications in pPb collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
76(7)
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2016
Measurement of the [Formula: see text] production cross section in the all-jets final state in pp collisions at [Formula: see text][Formula: see text].
The European physical journal. C, Particles and fields.
76
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Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung.
PloS one.
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2016
Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury.
Pulmonary circulation.
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2016
Nonmyeloablative Stem Cell Transplantation with Alemtuzumab/Low-Dose Irradiation to Cure and Improve the Quality of Life of Adults with Sickle Cell Disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
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2016
Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology.
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2016
Plasma metabolomic profile in fibrosing pulmonary sarcoidosis.
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33(1):29-38
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Racial Differences in Mortality from Severe Acute Respiratory Failure in the United States, 2008-2012.
Annals of the American Thoracic Society.
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Reactive oxygen species-associated molecular signature predicts survival in patients with sepsis.
Pulmonary circulation.
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Regulation of Thrombin-Induced Lung Endothelial Cell Barrier Disruption by Protein Kinase C Delta.
PloS one.
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Role of Nrf2 and Autophagy in Acute Lung Injury.
Current pharmacology reports.
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2016
Search for massive WH resonances decaying into the [Formula: see text] final state at [Formula: see text][Formula: see text].
The European physical journal. C, Particles and fields.
76(5)
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A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis.
BMC pulmonary medicine.
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A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing.
American journal of physiology. Lung cellular and molecular physiology.
309(9):L983-94
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A MYLK variant regulates asthmatic inflammation via alterations in mRNA secondary structure.
European journal of human genetics : EJHG.
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A nonmuscle myosin light chain kinase-dependent gene signature in peripheral blood mononuclear cells is linked to human asthma severity and exacerbation status.
Pulmonary circulation.
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c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
American journal of physiology. Lung cellular and molecular physiology.
308(10):L1025-38
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2015
Constraints on parton distribution functions and extraction of the strong coupling constant from the inclusive jet cross section in pp collisions at [Formula: see text][Formula: see text].
The European physical journal. C, Particles and fields.
75(6)
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2015
Constraints on the pMSSM, AMSB model and on other models from the search for long-lived charged particles in proton-proton collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
75(7)
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2015
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology.
308(2):L208-20
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2015
Distributions of topological observables in inclusive three- and four-jet events in pp collisions at [Formula: see text][Formula: see text].
The European physical journal. C, Particles and fields.
75(7)
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2015
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia.
Blood.
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2015
Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent.
The Journal of allergy and clinical immunology.
136(4):1116-8.e9
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2015
Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.
Human genetics.
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2015
Identifying Novel Biomarkers in Sarcoidosis Using Genome-Based Approaches.
Clinics in chest medicine.
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2015
Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury.
American journal of physiology. Lung cellular and molecular physiology.
309(11):L1294-304
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Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate.
Microvascular research.
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2015
Measurement of electroweak production of two jets in association with a Z boson in proton-proton collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
75(2)
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2015
Measurement of the differential cross section for top quark pair production in pp collisions at [Formula: see text].
The European physical journal. C, Particles and fields.
75(11)
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2015
Measurement of the inclusive 3-jet production differential cross section in proton-proton collisions at 7 TeV and determination of the strong coupling constant in the TeV range.
The European physical journal. C, Particles and fields.
75(5)
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2015
Measurements of differential and double-differential Drell-Yan cross sections in proton-proton collisions at [Formula: see text][Formula: see text].
The European physical journal. C, Particles and fields.
75(4)
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2015
Measurements of the [Formula: see text][Formula: see text] production cross sections in the [Formula: see text] channel in proton-proton collisions at [Formula: see text] and [Formula: see text] and combined constraints on triple gauge couplings.
The European physical journal. C, Particles and fields.
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Precise determination of the mass of the Higgs boson and tests of compatibility of its couplings with the standard model predictions using proton collisions at 7 and 8[Formula: see text].
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Measurement of top quark-antiquark pair production in association with a W or Z boson in pp collisions at [Formula: see text][Formula: see text].
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Search for heavy neutrinos and [Formula: see text] bosons with right-handed couplings in proton-proton collisions at [Formula: see text].
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CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
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Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes.
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Transactivation of sphingosine 1-phosphate receptors is essential for vascular barrier regulation. Novel role for hyaluronan and CD44 receptor family.
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The role of caldesmon in the regulation of endothelial cytoskeleton and migration.
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A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability.
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51(6):341-52
[DOI] 10.1136/jim-51-06-30.
[PMID] 14686637.
2003
Mutation analysis of the non-muscle myosin light chain kinase (MLCK) deletion constructs on CV1 fibroblast contractile activity and proliferation.
Journal of cellular biochemistry.
88(3):623-34
[PMID] 12532337.
2003
Phorbol esters increase MLC phosphorylation and actin remodeling in bovine lung endothelium without increased contraction.
American journal of physiology. Lung cellular and molecular physiology.
285(2):L415-26
[PMID] 12740219.
2003
Pulmonary vascular permeability and ischemic injury in gelsolin-deficient mice.
American journal of respiratory cell and molecular biology.
28(4):478-84
[PMID] 12654637.
2003
Rho family of guanine exchange factors (GEFs) in cellular activation: who’s dancing? And with whom?
Circulation research.
93(9):794-5
[PMID] 14592993.
2003
Role of Ca2+ in diperoxovanadate-induced cytoskeletal remodeling and endothelial cell barrier function.
American journal of physiology. Lung cellular and molecular physiology.
285(5):L1006-17
[PMID] 12882766.
2003
Role of CaM kinase II and ERK activation in thrombin-induced endothelial cell barrier dysfunction.
American journal of physiology. Lung cellular and molecular physiology.
285(1):L43-54
[PMID] 12788788.
2003
Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products.
American journal of physiology. Lung cellular and molecular physiology.
285(1):L258-67
[PMID] 12626332.
2003
S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin.
Journal of applied physiology (Bethesda, Md. : 1985).
94(3):1193-203
[PMID] 12482769.
2003
The role of the microtubules in tumor necrosis factor-alpha-induced endothelial cell permeability.
American journal of respiratory cell and molecular biology.
28(5):574-81
[PMID] 12707013.
2002
Critical involvement of p38 MAP kinase in pertussis toxin-induced cytoskeletal reorganization and lung permeability.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
16(9):1064-76
[PMID] 12087068.
2002
Hepatocyte growth factor enhances endothelial cell barrier function and cortical cytoskeletal rearrangement: potential role of glycogen synthase kinase-3beta.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
16(9):950-62
[PMID] 12087056.
2002
Leukocyte-induced microvascular permeability: how contractile tweaks lead to leaks.
Circulation research.
90(11):1143-4
[PMID] 12065313.
2002
Novel interaction of cortactin with endothelial cell myosin light chain kinase.
Biochemical and biophysical research communications.
298(4):511-9
[PMID] 12408982.
2002
Phospholipase D activation by sphingosine 1-phosphate regulates interleukin-8 secretion in human bronchial epithelial cells.
The Journal of biological chemistry.
277(33):30227-35
[PMID] 12039947.
2002
Role of tyrosine kinase signaling in endothelial cell barrier regulation.
Vascular pharmacology.
39(4-5):201-12
[PMID] 12747960.
2002
Serum factors involved in human microvascular endothelial cell morphogenesis.
The Journal of laboratory and clinical medicine.
140(3):188-98
[PMID] 12271276.
2002
Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells.
American journal of respiratory cell and molecular biology.
26(4):453-64
[PMID] 11919082.
Grants
Sep 2024
ACTIVE
Coronary Microvascular Disease in Diabetes: Role of NAMPT
Role: Co-Investigator
Funding: US ARMY MED RES ACQUISITION
Apr 2024
– May 2024
Novel Involvement of NAMPT and TLR4 in PAH Vascular Remodeling
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Sep 2023
ACTIVE
Cytoskeletal Regulation of Lung Endothelial Pathobiology in ARDS
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Aug 2023
ACTIVE
Novel mechanism for eNAMPT secretion in PAH vascular remodeling
Role: Other
Funding: NATL INST OF HLTH NIA
Apr 2023
– Mar 2024
Validation of a Genetic-based Biomarker Panel for Stratification of Mortality Risk in ARDS Patients
Role: Principal Investigator
Funding: UNIVERSITY OF ARIZONA
via NATL INST OF HLTH NHLBI
Jan 2023
– Feb 2024
Coronary Microvascular Disease in Diabetes: Role of NAMPT
Role: Principal Investigator
Funding: UNIV OF CALIFORNIA SAN DIEGO
via US ARMY MED RES ACQUISITION
Contact Details
Phones:
- Business:
- (561) 228-2030
Emails:
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- jgn.garcia@ufl.edu
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