Alicia Angelbello, Ph.D., a student of the Skaggs Graduate School, studied with UF Scripps Chemistry Department Chair Matthew Disney, Ph.D. She has been awarded the American Chemical Society’s Nobel Signature Award. UF Scripps Chemist Matthew Disney and Skaggs Graduate School student Alicia Angelbello devised a way to potentially treat a…
Rumbaugh lab found that the gene Syngap1 enables normally quiet neurons to spring into activity during sensory challenges, while other neurons are quieted.
Kendall Nettles, PhD, (center) meets with two students in his lab, Jacqline Njeri (left) and Charles Min (right). Nettles and colleagues designed drug-like molecules that appear to fight estrogen-sensitive breast cancer in two ways, in cell studies. Njeri and Min are co-authors on the paper, published August 27, 2021, in…
Like a carpenter switching drill bits depending on the job at hand, scientists at Scripps Research in Florida have changed an investigational medicine’s activity by swapping in different molecular tools, in the process, showing a potential new way to address multiple incurable diseases.
The scientists have devised a way to lock HIV in its dormant stage. Now they want to throw away the key.
If KIF5C is knocked out, the team found, the neurons’ ability to branch out dendrites and form input-receiving spines suffers.
When the brain’s synapses are activated, they set off a signaling cascade that results in the expression of long noncoding RNA called “ADEPTR.” The RNA is quickly transported along dendrites to synapses, where it acts on proteins involved in remodeling. (Image courtesy of Jenna Wingfield and Yibo Zhao of the…
Mutations to Dyrk1a gene lead to brain undergrowth with features of autism and intellectual disability. An existing drug rescues the condition in newborn mice, Scripps Florida scientists find.
Study reveals how T cells in the small intestine respond to bile acids, offering localized treatment direction for a cause of chronic illness.
Subramaniam shows that the mutated huntingtin protein slows brain cells’ protein-building machines, called ribosomes.