First-of-Its-Kind Compound Targets Lung Cancer Cells
A first-of-its-kind anti-cancer compound from the Chapman lab targets a heat shock protein found in some lung cancers.
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Inventions
ARDS Patients Improve with Experimental Treatment
A proof-of-concept study suggests a monoclonal antibody could offer much-needed treatment for ARDS.
Researchers Tether Cancer-Killing Natural Product to Cancer-Targeting Antibodies
A team led by chemistry professor Ben Shen, Ph.D., discovered a potent anti-cancer compound within the institute's natural products collection. It has been connected to a precise cancer-seeking antibody with an innovative linker molecule.
Mining Natural Products Reveals Nature’s Method for Building a Cancer Killer
Enediynes can bind and break DNA, leading to cell death. As a result, they have enormous potential as antibiotics and cancer drugs. A new study reveals how nature assembles them.
Outstanding UF Scripps Inventors Recognized by UF Innovate
Two scientists at UF Scripps have been recognized with "Invention of the Year" awards from UF Innovate. Read about their inventions.
Scientists Look to Nature to Discover Method for Installing Sulfur Into Complex Molecules
The natural products collection at Scripps Florida contains hundreds of thousands of organisms available for study. Advance provides new tools for synthetic chemists and biologists looking to probe and modify sulfur-based biochemistry JUPITER, FL—A group of highly reactive compounds called persulfides have provoked great curiosity…
Research on Hormone Receptors Advances Understanding of Sensitive Cancers
By distorting estrogen receptor shape in two different ways, compounds offer a two-for-one punch to estrogen-sensitive cancer cells. Kendall Nettles, PhD, (center) meets with two students in his lab, Jacqline Njeri (left) and Charles Min (right). Nettles and colleagues designed drug-like molecules that appear to fight estrogen-sensitive breast cancer in…
A New Approach to Curing HIV: Armed with a $26.5-Million Grant, A Multi-Institution Collaboration Tackles HIV in a New Way
The scientists have devised a way to lock HIV in its dormant stage. Now they want to throw away the key.
Autism gene study finds widespread impact to brain’s growth signaling network
Mutations to Dyrk1a gene lead to brain undergrowth with features of autism and intellectual disability. An existing drug rescues the condition in newborn mice, Scripps Florida scientists find.
Toward Safer Steroids
Scientists devise process for making precision anti-inflammatory medicines with fewer side-effects at UF Scripps Biomedical Research in Jupiter, Florida.
