What scientists thought they knew about an important TB enzyme is wrong. "It acts in a completely different way," says Luiz Pedro Carvalho, Ph.D. His research appears in the journal PNAS.
AI can help us search enormous numbers of chemical structures. But it cannot look at a patient waiting for a medicine and decide which problem is worth a life's work.
A new approach to "molecular glue" drug design snags an "undruggable" diabetes target.
Federal grants worth up to $7.4 million will boost research on treatments for mosquito-borne viral diseases.
For "outstanding lifetime contributions to natural products chemistry," and "significantly improving medicine and human health," with RNA-targeting innovations, two prestigious awards go to Wertheim UF Scripps scientists.
An international grant to Thomas Kodadek, Ph.D., will advance his lab’s work on molecular glue degraders for incurable diseases.
Mapping vulnerabilities in the SARS-CoV-2 genome, made of RNA, reveals a path to fighting more than COVID-19.
"These grants highlight The Wertheim UF Scripps Institute’s unique expertise in areas that include neuroscience, immunology, biochemistry, drug discovery and RNA therapeutics,” said Scientific Director Patrick Griffin, Ph.D.
Liu’s research focuses on the discovery of small molecules for human proteins, as well as the functional characterization of these proteins in physiological and disease contexts.
A cancer-killing compound, called tiancimycin, combined with a cancer-seeking antibody, shows promise against an aggressive type of lymphoma.
